ESR 15 – DEVELOPMENT OF A BIOINFORMATICS SOFTWARE SUITE FOR SINGLE CELL GENOMICS DATA ANALYSIS
Research project
Generating automatic bioinformatics pipelines for obtaining quality results from huge data packages from Single Cell Next-Generation Sequencing (NGS) data has become key for the advance of biological discoveries.
The main objectives of the Early Stage Researcher (ESR15) are:
I. Generate a set of automatic bioinformatics pipelines that will allow all the research community to analyze single-cell genomics, transcriptomics and metabolomics data with very little computational biology knowledge.
II. Create a visual framework and back-end database in order to link the most well- known and curate databases with the NGS data results, and allow the researchers to interact and generate downstream discoveries.
III. Deploy and maintain a bioinformatics suit Software as a Service (SaaS) for Singe Cell Genomics.
We expect that generating a robust and scientifically validated automatic bioinformatics system for analysing, organizing and visualizing single-cell genomics, transcriptomics and metabolomics will help the research community to increase the usage and adoption of single-cell high-throughput genomic studies.Supervisor
Albert Mascarell (amascarell@ascidea.com)
Early Stage Researcher
Host institution and location
PhD Program
The Early Stage Researcher in this case will not be asked to get a PhD after the 3 years.
Expected Results
A set of automatic bioinformatics tools for the analysis of single-cell NGS data. Database structures and a front-end implementation for NGS data analysis, organisation and visualisation allowing a workspace framework for researchers.
Planned secondments
CRG-CNAG – Month 19 (3 m) – Bioinformatics on single gene genomics
CNRS-R – Month 28 (3 m) – Bioinformatic analysis and databases for SCG and metagenomics
CSIC-IBE – Month 36 (3 m) – SAG databases and tools for genome screening